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2 papers
Recent·Most cited
M. E. Torki, F. Liu, R. Xu, Y. Chen, J. Fredberg, Z. Chen
This paper introduces a trizonal model to predict cancer cell shape transitions under ECM stiffening, revealing three motility zones and their implications for invasion.
bioRxiv · Dec 2, 2023 · PreprintCell Biology
S. HE, C. V. Carman, J. H. Lee, B. Lan, S. Koehler, L. Atia, C. Y. Park, J. H. Kim, J. A. Mitchel, J.-A. Park, J. P. Butler, S. W. Lee, J. Fredberg
This study shows that p53 loss decreases single-cell motility and invasion in 2-D and 3-D assays, but promotes collective cellular migration in spheroids.
bioRxiv · Jul 30, 2018Cancer Biology