Author

J. Griffiths

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:Arabidopsis· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Al-Shamkhani· 1 shared A. Hoyle· 1 shared A. L. Tutt· 1 shared A. M. Jones· 1 shared A. M. Piskorz· 1 shared A. Rizza· 1 shared A. Sawle· 1 shared A.-M. Mes-Masson· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. Al-Shamkhani

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Gibberellin Perception Sensors 1 and 2 reveal cellular GA dynamics articulated by COP1 and GA20ox1 that are necessary but not sufficient to pattern hypocotyl cell elongation

J. Griffiths, A. Rizza, B. Tang, W. B. Frommer, A. M. Jones

The paper uses a GA biosensor to show COP1 and GA20ox1 regulate GA gradients in hypocotyls, which are necessary but not sufficient for cell elongation during light and dark conditions.

bioRxiv · Nov 6, 2023 · PreprintPlant Biology

Molecular landscape and functional characterization of centrosome amplification in ovarian cancer

C. M. Sauer, J. A. Hall, D.-L. Couturier, T. Bradley, A. M. Piskorz, J. Griffiths, A. Sawle, M. D. Eldridge, P. Smith, K. Hosking, M. A. Reinius, L. Morrill Gavarro, A.-M. Mes-Masson, D. Ennis, D. Millan, , J. D. Brenton

This study identifies centrosome amplification as a common and heterogeneous feature in HGSOC, linked to CIN and treatment resistance.

bioRxiv · Sep 13, 2022Cancer Biology

Domain Binding and Isotype Dictate the Activity of Anti-human OX40 Antibodies

J. Griffiths, K. Hussain, H. L. Smith, T. Sanders, K. Cox, M. Semmrich, L. Martennson, J. Kim, T. Inzhelevskaya, C. Penfold, A. L. Tutt, I. Mockridge, C. H. Chan, V. English, R. R. French, , M. S. Cragg

This study evaluates how isotype and epitope of anti-human OX40 antibodies affect their therapeutic activity in tumor models.

bioRxiv · Jun 29, 2020Immunology