Increased epithelial mTORC1 activity in chronic rhinosinusitis with nasal polyps
N. A. Barrett, G. X. Huang, N. R. Hallen, M. Lee, K. Zheng, X. Wang, M. V. Mandanas, S. Djeddi, D. Fernandez, J. Hacker, T. Ryan, R. W. Bergmark, N. Bhattacharyya, S. Lee, A. Z. Maxfield, , M. Gutierrez-Arcelus
The paper identifies increased mTORC1 activity in CRSwNP epithelial cells and links it to cytokine production and inflammation in both CRSwNP and asthma.
bioRxiv · Oct 13, 2023 · PreprintImmunology