K. Zheng

This study shows mitochondrial respiration is essential for ATP supply to the cytosol in photosynthesizing plant cells, using moss as a model.

This study develops sex-specific computational models to analyze how diuretics affect renal electrolyte transport differently in male and female rats under hypertension.

The paper identifies extensive proteolytic processing of plant proteins in agroinfiltrated N. benthamiana using peptographs and mass spectrometry, revealing widespread proteoform modifications.

The paper identifies increased mTORC1 activity in CRSwNP epithelial cells and links it to cytokine production and inflammation in both CRSwNP and asthma.

The paper shows that CXCR3 chemokines use different phosphorylation barcodes to activate distinct signaling pathways, leading to varied physiological outcomes.

The paper shows E6AP is critical for HPV E6 regulation of epithelial homeostasis, with its loss impairing keratinocyte differentiation and YAP activation.

The paper shows that biased CXCR3 agonists produce different signaling outcomes based on subcellular location, with endosomal signaling playing a key role in biased activation.

This study investigates how Alisertib affects KRAS mutations in colorectal cancer cells, showing allele-specific effects on RAS signaling and cell death mechanisms.

This study validates spray-dried mesoporous bioactive glass microspheres as a prolonged BMP-2 release system to enhance bone regeneration with reduced side effects.

This study shows that enhanced RNA-directed DNA methylation (RdDM) in reproductive organs increases DNA methylation, ensuring sexual reproduction in rice by regulating gene expression.

This study shows that SIRT1 and SIRT6 work together to recognize DNA breaks and enhance the DNA damage response and repair.

The paper demonstrates that Gαi proteins can form complexes with β-arrestin, independent of their canonical G protein coupling, and these complexes can bind GPCRs and ERK.

The paper shows lncRNAs and circRNAs sponge miRNAs to maintain Oct4 expression during reprogramming, enhancing reprogramming efficiency.

This study shows that gut microbiota influences biliary regenerative responses in mice, with butyrate playing a role in inhibiting fibrosis.

This study shows that PLEKHO1 in osteoblasts worsens joint inflammation in RA and promotes bone formation, suggesting it as a therapeutic target.

The paper identifies two CRISPR-Cas VI-B systems with Cas13b and characterizes their RNA interference activity and regulation by Csx27 and Csx28.