Author

J. Hastie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. Knebel· 1 shared C. Johnson· 1 shared D. Durocher· 1 shared F. Brown· 1 shared F. Lamoliatte· 1 shared G. Pastore· 1 shared J. Rouse· 1 shared M. Gregorczyk· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. Knebel

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 31, 2022

Interaction with C21ORF2 controls the cellular functions of the NEK1 kinase

J. Rouse, M. Gregorczyk, G. Pastore…·D. Durocher

This study identifies C21ORF2 as a regulatory subunit of NEK1, showing that their interaction is critical for NEK1 function and that mutations disrupt this interaction, linking it to disease.

DOI 10.1101/2022.08.31.505651

humanexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivNov 29, 2017

The MALDI TOF E2/E3 ligase assay as an universal tool for drug discovery in the ubiquitin pathway

V. De Cesare, C. Johnson, V. Barlow…·M. Trost

The paper introduces a MALDI TOF-based assay for high-throughput screening of E2/E3 ligase activity in the ubiquitin pathway, demonstrating its utility for drug discovery.

DOI 10.1016/j.chembiol.2018.06.004

experimental assaydrug response / drug discovery

𝕏 PostBluesky