J. J. Choi

This study observes microbubble dynamics in brain microvessels using high-speed microscopy, showing they can exert mechanical stress on tissue and extravasate under ultrasound exposure.

The paper identifies a neuro-responsive subset of muscle stem cells that support neuromuscular junction integrity during aging and neurodegeneration.

This study shows that motor neurons enhance muscle stem cell function by boosting protein synthesis and mitochondrial activity, which is critical for muscle regeneration and is disrupted in diseases like muscular dystrophy and aging.

This study shows that transplanting healthy muscle stem cells into dystrophic muscle improves mitochondrial function and bioenergetics, while compromised stem cells fail to do so.

This study develops an in vitro muscle parabiosis system to identify rejuvenating factors in aged muscle stem cells by mimicking systemic and local signals.

This study investigates how critical limb ischemia affects skeletal muscle by increasing myonuclear number and mitochondrial content per myonucleus in mice.