Author

J. J. Crowe

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Immunology· 1

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:mouse· 1

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B. J. Lee· 1 shared S. Zha· 1 shared V. Estes· 1 shared X. Wang· 1 shared Z. Shao· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperImmunology

B. J. Lee

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1 paper

Recent·Most cited

ImmunologybioRxivApr 23, 2020

DNA-PKcs phosphorylation at the T2609 cluster alters the repair pathway choice during immunoglobulin class switch recombination

J. J. Crowe, X. Wang, Z. Shao…·S. Zha

This study shows that DNA-PKcs phosphorylation at T2609 cluster promotes cNHEJ repair pathway choice during CSR, as loss of this phosphorylation increases chromosomal translocation and alternative end-joining.

DOI 10.1073/pnas.2007455117

mouseDNA methylation

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