Author

V. Vijayan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2 Biophysics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Assay:proteomics· 4 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

A. Elezaby· 2 shared B. Haileselassie· 2 shared D. Mochly-Rosen· 2 shared N. P. Ostberg· 2 shared A. Bertaina· 1 shared A. Gokhale· 1 shared A. J. Lin· 1 shared A. Kilic· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

A. Elezaby

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Phase separation of second prion domain of CPEB3: Insights from the aggregation and structural studies

V. Vijayan, D. S. Reselammal, F. Pinhero, A. Sandeep

This study investigates the aggregation and structural properties of the second prion domain of mouse CPEB3, finding that it undergoes phase separation forming stable, amyloid-like solid condensates.

bioRxiv · Apr 1, 2024 · PreprintBiophysics

Extracellular release of damaged mitochondria induced by pre-hematopoietic stem cell transplant conditioning exacerbates graft-versus-host disease

V. Vijayan, H. Yan, J. K. Lohmeyer, K. A. Prentiss, R. V. Patil, G. Barbarito, I. Lopez, A. Elezaby, K. Peterson, J. Baker, N. P. Ostberg, A. Bertaina, R. S. Negrin, D. Mochly-Rosen, K. Weinberg, B. Haileselassie

This study shows that conditioning before hematopoietic stem cell transplant releases damaged mitochondria, which activate host APCs and worsen GVHD.

bioRxiv · Apr 24, 2023 · PreprintImmunology

Cardiac Troponin I Directly Binds and Inhibits Mitochondrial ATP Synthase: a Noncanonical Role in the Post-Ischemic Heart

A. Elezaby, A. J. Lin, V. Vijayan, S. Pokhrel, L. R. Bechara, N. P. Ostberg, B. B. Queliconi, J. C. Campos, J. C. Ferreira, B. Haileselassie, D. Mochly-Rosen

This study identifies a noncanonical role of cardiac troponin I in inhibiting mitochondrial ATP synthase, showing that blocking this interaction reduces cardiac injury during ischemia.

bioRxiv · Feb 3, 2023Cell Biology

Parkinson mutations in DNAJC6 cause lipid defects and neurodegeneration that are rescued by Synj1

J. Jacquemyn, S. Kuenen, J. Swerts, B. Pavie, V. Vijayan, A. Kilic, D. Chabot, Y.-C. Wang, N. Schoovaerts, P. Verstreken

This study shows that Parkinson's mutations in DNAJC6 cause lipid defects and neurodegeneration in Drosophila, which are rescued by overexpressing Synj1.

bioRxiv · Apr 27, 2022 · PreprintCell Biology

RelCoVax(R), a two antigen subunit protein vaccine candidate against SARS-CoV-2 induces strong immune responses in mice

A. Phatarphekar, G. V. Reddy, A. Gokhale, G. Karanam, P. Kuchroo, K. Shinde, G. Masand, S. Pagare, N. Khadpe, S. S. Pai, V. Vijayan, R. RL, K. P. Reddy, P. Rao, S. H. Rao, V. Ramana

RelCoVax(R), a dual RBD and N subunit vaccine, induces strong antibody and Th1 cellular responses and neutralizes SARS-CoV-2 strains in mice.

bioRxiv · Jan 7, 2022Immunology

Trade-offs between host tolerances to different pathogens in plant-virus interactions

N. montes, V. Vijayan, I. Pagan

The paper tests if tolerance to one virus trades off against tolerance to others in Arabidopsis thaliana, finding virulence-dependent trade-offs between tolerance to TuMV and CMV.

bioRxiv · Oct 9, 2019Evolutionary Biology