ImmunologybioRxivPreprint
Extracellular release of damaged mitochondria induced by pre-hematopoietic stem cell transplant conditioning exacerbates graft-versus-host disease
V. Vijayan, H. Yan, J. K. Lohmeyer…·B. Haileselassie
This study shows that conditioning before hematopoietic stem cell transplant releases damaged mitochondria, which activate host APCs and worsen GVHD.