Author

J. Klein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Microbiology· 2 Cell Biology· 1 Ecology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 5 Approach:experimental assay· 4 Organism:mouse· 3 Approach:statistical model· 3 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Iwasaki· 3 shared B. Israelow· 2 shared E. Song· 2 shared T. Mao· 2 shared A. Antonelli· 1 shared A. Casanovas-Massana· 1 shared A. Cassanovas-Massana· 1 shared A. I. Ko· 1 shared

Activity by Year

2020-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

A. Iwasaki

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Sexual reproduction contributes to the evolution of resistance breaking isolates of the spinach pathogen Peronospora effusa

P. Skiadas, J. Klein, T. Quiroz Monnens, J. Elberse, R. de Jonge, G. Van den Ackerveken, M. F. Seidl

This paper analyzes the genetic diversity of Peronospora effusa isolates to show that they evolve through both asexual and sexual reproduction, contributing to the emergence of resistance-breaking races.

bioRxiv · Nov 5, 2021Evolutionary Biology

Systematic Discovery of Antibacterial and Antifungal Bacterial Toxins

N. Nachmias, N. Dotan, R. Fraenkel, M. C. Rocha, M. Kluzek, M. Shalom, A. Rivitz, N. Shamash-Halevy, I. Cahana, N. Deouell, J. Klein, N. Schlezinger, N. Tzarum, Y. Oppenheimer-Shaanan, A. Levy

The paper identifies novel bacterial toxins and their immunity genes, showing antifungal activity and enzymatic function.

bioRxiv · Oct 19, 2021Microbiology

Gut microbiome dysbiosis during COVID-19 is associated with increased risk for bacteremia and microbial translocation.

M. Venzon, L. Bernard-Raichon, J. Klein, J. E. Axelrad, C. Zhang, G. A. Hussey, A. P. Sullivan, A. Cassanovas-Massana, M. G. Noval, A. M. Valero-Jimenez, J. Gago, G. Putzel, A. Pironti, E. Wilder, Yale IMPACT Research Team, , J. Schluter

The paper shows that gut microbiome dysbiosis in COVID-19 patients is linked to increased risk of bacteremia and microbial translocation.

bioRxiv · Jul 15, 2021 · PreprintMicrobiology

Adaptive immune determinants of viral clearance and protection in mouse models of SARS-CoV-2

B. Israelow, T. Mao, J. Klein, E. Song, B. Menasche, S. B. Omer, A. Iwasaki

The paper investigates the roles of humoral and cellular immunity in SARS-CoV-2 clearance and protection against a variant, finding antibodies mediate protection in both vaccinated and naturally infected mice.

bioRxiv · May 19, 2021Immunology

Exploratory neuroimmune profiling identifies CNS-specific alterations in COVID-19 patients with neurological involvement

E. Song, C. M. Bartley, R. D. Chow, T. Ngo, R. Jiang, C. R. Zamecnik, R. Dandekar, R. Loudermilk, Y. Dai, F. Liu, I. Hawes, B. D. Alvarenga, T. Huynh, L. McAlpine, N.-T. Rahman, , S. F. Farhadian

The paper identifies CNS-specific immune alterations in COVID-19 patients with neurological symptoms, suggesting neuroinvasion and anti-neural autoimmunity as potential causes.

bioRxiv · Sep 11, 2020Immunology

Exploring the impact of political regimes on biodiversity

A. Zizka, O. Ryden, D. Edler, J. Klein, H. Aronsson, A. Perrigo, D. Silvestro, S. C. Jagers, S. I. Lindberg, A. Antonelli

The paper quantifies how different political regimes affect biodiversity management by linking democracy levels to natural history specimen registrations.

bioRxiv · Feb 25, 2020 · PreprintEcology

Enhanced stress tolerance through reduction of G3BP and suppression of stress granules

A. K. Lee, J. Klein, K. Fon Tacer, T. Lord, M. L. Oatley, J. M. Oatley, S. N. Porter, S. M. Pruett-Miller, E. B. Tikhonova, A. L. Karamyshev, P. Yang, H. J. Kim, J. P. Taylor, P. R. Potts

This study shows that MAGE-B2 enhances stress tolerance by reducing G3BP and suppressing stress granules, protecting male germline cells from heat stress.

bioRxiv · Feb 3, 2020 · PreprintCell Biology