Author

J. Krell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:clustering· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

B. Kaur· 2 shared C. Sokota· 2 shared D. P. Ennis· 2 shared G. Giannone· 2 shared J. McDermott· 2 shared N. Singh· 2 shared Z. Cheng· 2 shared A. Piskorz· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCancer Biology

B. Kaur

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2 papers

Recent·Most cited

The genomic trajectory of ovarian high grade serous carcinoma is determined in STIC lesions

Z. Cheng, D. P. Ennis, B. Lu, H. B. Mirza, C. Sokota, B. Kaur, N. Singh, O. Le Saux, G. Russo, G. Giannone, L. A. Tookman, J. Krell, J. McDermott, C. Barnes, I. A. McNeish

This study shows that high ploidy and whole genome duplication in ovarian high-grade serous carcinoma originate in STIC lesions, indicating early determination of the tumor's genomic trajectory.

bioRxiv · Mar 11, 2024 · PreprintCancer Biology

The genomic landscape of early stage ovarian high grade serous carcinoma

Z. Cheng, H. Mirza, D. P. Ennis, P. Smith, L. Morrill, C. Sokota, G. Giannone, T. Goranova, T. Bradley, A. Piskorz, M. Lockley, The BriTROC Investigators, B. Kaur, N. Singh, L. Tookman, , I. McNeish

This study compares genomic features of early and late stage high grade serous ovarian carcinoma, finding no unique mutations or focal copy number alterations but noting differences in ploidy and copy number signatures.

bioRxiv · May 5, 2021Cancer Biology