J. M. Kimmey

This study shows that ATG5 suppresses type I IFN-induced neutrophil swarming and NETosis during M. tuberculosis infection, contributing to disease susceptibility when ATG5 is absent.

This study shows that ATG5 in CD11c+ cells suppresses pro-inflammatory cytokines and neutrophil recruitment during M. tuberculosis infection without affecting pathogen replication.

This study identifies that the Pseudomonas aeruginosa protease LasB directly activates IL-1β independently of inflammasomes, contributing to lung inflammation and pathology during infection.

This study uses CRISPRi-seq to identify genetic factors important for Streptococcus pneumoniae pneumonia, revealing a critical bottleneck at 48 h post-infection and gene fitness differences between in vitro and in vivo conditions.