PhysiologybioRxivPreprint
Soluble guanylate cyclase stimulation mitigates skeletal and cardiac muscle dysfunction in a mdx model of Duchenne muscular dystrophy
L. Zhang, Y. Xu, K. Yousefi…·J. M. Percival
This study shows that stimulating soluble guanylate cyclase (sGC) with BAY41-8543 reduces skeletal and cardiac muscle dysfunction in mdx mice, suggesting sGC as a therapeutic target for Duchenne muscular dystrophy.
DOI 10.1101/2021.02.14.431156