J. M. Schrader

This study shows that RNase E autoregulation in Caulobacter crescentus involves phase-separation and 5 UTR cleavage, enhancing fitness through proper mRNA decay control.

The paper identifies 111 proteins enriched in bacterial RNP bodies (BR-bodies) and shows they form a complex network of protein-protein and protein-RNA interactions that regulate BR-body phase separation and RNA processing.

The paper investigates how mRNA accessibility distinguishes initiator AUGs from elongator AUGs in C. crescentus by analyzing Shine-Dalgarno site function and RNA secondary structures.

This study shows RNase E biomolecular condensates enhance PNPase activity, accelerating RNA decay and shaping the transcriptome.

Rif-Correct improves mRNA half-life estimation in Rif-seq data by accounting for transcriptional runoff using transcriptome models.

The paper identifies RNA substrates of BR-bodies and shows they stimulate mRNA decay while preventing toxic intermediates.

This study uses RNA-Seq to analyze the global transcriptome of Myxococcus xanthus during its multicellular developmental program, revealing gene expression patterns and regulatory networks.

The paper measures mRNA translation in C. crescentus using ribosome profiling, finding that B12-related genes account for ~4.5% of protein synthesis and reveal fitness costs of B12 scavenging.

This study uses microscopy to show RNase E and ribosomes are spatially organized in Caulobacter crescentus, with clustering linked to RNA availability and rRNA gene location.