J. Perez

Two antagonistic gene regulatory networks drive Arabidopsis root hair growth at low temperature

This paper identifies two opposing gene regulatory networks that control root hair growth in Arabidopsis at low temperature, revealing their role in integrating environmental and internal signals.

Dissociable contributions of basolateral amygdala and ventrolateral orbitofrontal cortex to flexible learning under uncertainty

This study investigates the distinct roles of vlOFC and BLA in stimulus- and action-based reversal learning under uncertainty using chemogenetic inhibition in rats.

Coupling remote sensing and eDNA to monitor environmental impact: A pilot to quantify the environmental benefits of sustainable agriculture in the Brazilian Amazon

The paper develops and applies a coupled remote sensing and eDNA approach to assess the environmental impact of sustainable agriculture in the Brazilian Amazon.

Morphological limitations imposed on lizards facing urbanization

This study examines how urbanization filters lizard morphologies, finding that urban-tolerant species have reduced morphological diversity compared to natural species.

Separating the effects of sex hormones and sex chromosomes on behavior in the African pygmy mouse Mus minutoides, a species with XY female sex reversal.

This study investigates how sex chromosomes and hormones influence behavior in Mus minutoides by comparing hormone levels across different sex genotypes.

Heterologous Expression of NoxA Confers Aerotolerance in Clostridium sporogenes

This study introduces aerotolerance to C. sporogenes by expressing the NoxA gene from C. aminovalericum, enhancing its viability in oxygenated environments for cancer therapy and biomanufacturing.

Genotypic sex shapes maternal care in the African Pygmy mouse, Mus minutoides

The paper shows that genotypic sex, not just gonadal hormones, influences maternal care in African pygmy mice, revealing a third female genotype with distinct care strategies and neural impacts.

Multiple Sex Chromosome Drivers in a Mammal with Three Sex Chromosomes

The paper investigates sex chromosome drive in Mus minutoides, showing male Y chromosome transmission varies based on mating partner genotype, stabilizing a feminizing X chromosome.

Timing of transcriptomic peripheral blood mononuclear cell responses of sheep to Fasciola hepatica infection differs from those of cattle, reflecting different disease phenotypes

This study compares the transcriptomic responses of sheep and cattle PBMC to Fasciola hepatica infection, finding differences in gene expression and pathway activation that reflect distinct disease outcomes.

Endomembrane targeting of human OAS1 p46 augments antiviral activity

This study shows that the OAS1 p46 isoform, targeted to the endomembrane system, enhances antiviral activity against RNA viruses and is associated with COVID-19 severity.

Fibroblasts as an Alternative to Mesenchymal Stem Cells with Successful Treatment and Immune Modulation in EAE Model of Multiple Sclerosis

This study shows fibroblasts can modulate the immune system and treat EAE, a multiple sclerosis model, by inhibiting T cell activation and promoting Treg cells, suggesting their potential as an alternative to MSCs.

SAXS Curves of Detergent Micelles: Effects of Asymmetry, Shape Fluctuations, Disorder, and Atomic Details

The paper investigates how atomic details, asymmetry, shape fluctuations, and disorder affect SAXS curves of DDM micelles using simulations and experiments.

Global transcriptome analysis of the Myxococcus xanthus multicellular developmental program

This study uses RNA-Seq to analyze the global transcriptome of Myxococcus xanthus during its multicellular developmental program, revealing gene expression patterns and regulatory networks.

Intrinsic checkpoint deficiency during cell cycle re-entry from quiescence

The paper shows that human cells re-entering the cell cycle from quiescence have impaired p53-dependent origin licensing and slow MCM loading, leading to underlicensed first S phases and increased replication stress sensitivity.