Premature Aging and Reduced Cancer Incidence Associated with Near-Complete Body-Wide Myc Inactivation
H. Wang, J. Lu, T. Stevens, A. Roberts, J. Mandel, R. Avula, B. Ma, Y. Wu, J. Wang, T. Finkel, C. Van't Land, J. E. Vockley, M. Airik, R. Airik, R. Muzumdar, , E. V. Prochownik
This study investigates the effects of near-complete Myc inactivation in mice, finding premature aging features but reduced cancer incidence and linking Myc dysregulation to aging and cancer.
bioRxiv · Jan 30, 2023 · PreprintCancer Biology