BiochemistrybioRxiv
Structures of the PKA RIα holoenzyme with the FLHCC driver J-PKAcα or wild type PKAcα
B. Cao, T.-W. Lu, J. Martinez Fiesco…·P. Zhang
This paper reports the crystal structures of J-PKAc fusion and wild-type PKA holoenzymes, revealing structural differences and conformational dynamics that may impact their function in FLHCC.
DOI 10.1016/j.str.2019.03.001