ImmunologybioRxiv
DNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8+ T cells
Z. Yu, V. Sasidharan-Nair, A. Bonifacius…·J. Huehn
The paper identifies TBKBP1 as a key gene whose demethylation enhances cytotoxic activity in CMV-specific CD8+ T cells, suggesting it as a therapeutic target.
DOI 10.1371/journal.ppat.1012581