Author

J. Pierce

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. J. Murphy· 1 shared A. O. Perantoni· 1 shared B. Paten· 1 shared B. Y. Winer· 1 shared D. Haussler· 1 shared D. K. Ma· 1 shared H. Correa· 1 shared H. M. Phelps· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCancer Biology

A. J. Murphy

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Author profile →

3 papers

Recent·Most cited

Suppressing APOE4-induced mortality and cellular damage by targeting VHL

W. Jiang, Y. Cao, Y. Xue, Y. Ji, B. Y. Winer, M. Zhang, N. S. Singhal, J. Pierce, S. Chen, D. K. Ma

This study shows that targeting the VHL-HIF axis suppresses mortality and cellular damage caused by APOE4 and other stressors in C. elegans and mice.

bioRxiv · Feb 28, 2024 · PreprintPhysiology

Exploiting Embryonic Niche Conditions to Grow Wilms Tumor Blastema in Culture

H. Wojcik, H. N. Lovvorn, M. Hollingshead, J. Pierce, H. Stotler, A. J. Murphy, S. Borgel, H. M. Phelps, H. Correa, A. O. Perantoni

This study develops a culture system to propagate Wilms Tumor blastemal cells using conditions that support nephron progenitor cell growth, enabling drug screening for cancer stem cells.

Frontiers in Oncology · Mar 16, 2023Peer-reviewedCancer Biology

KRAB Zinc Finger Proteins coordinate across evolutionary time scales to battle retroelements

J. D. Fernandes, M. Haeussler, J. Armstrong, K. Tigyi, J. Gu, N. Filippi, J. Pierce, T. Thisner, P. Angulo, S. Katzman, B. Paten, D. Haussler, S. Salama

The paper examines the evolutionary arms race between KRAB Zinc Finger Proteins (KZNFs) and retrotransposable elements (RTEs), showing how KZNFs adapt to suppress RTEs over time.

bioRxiv · Sep 27, 2018 · PreprintEvolutionary Biology