Author

J. Ratcliff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

P. Simmonds· 2 shared A. J. Mentzer· 1 shared A. McMichael· 1 shared B. M. Kessler· 1 shared C. Conlon· 1 shared C. Dold· 1 shared C. Liu· 1 shared D. Dong· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

P. Simmonds

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2 papers

Recent·Most cited

Evaluation of Different PCR Assay Formats for Sensitive and Specific Detection of SARS-CoV-2 RNA

J. Ratcliff, D. Nguyen, M. Andersson, P. Simmonds

The paper evaluates different PCR formats for SARS-CoV-2 RNA detection, finding that nested PCR with agarose gel electrophoresis is sensitive and specific but has variable sensitivity depending on transcript length.

bioRxiv · Jun 24, 2020 · PreprintMicrobiology

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients.

T. Dong, Y. Peng, A. J. Mentzer, G. Liu, X. Yao, Z. Yin, D. Dong, W. Dejnirattisai, L. Turtle, T. Rostron, K. Subramaniam, P. Thomson, P. Zhang, C. Dold, J. Ratcliff, , Lopez-C

This study examines T cell immunity in UK COVID-19 patients, finding stronger and broader memory T cell responses in severe cases, with implications for vaccine design.

bioRxiv · Jun 5, 2020Immunology