Author

J. Beeson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J.-A. Chan· 3 shared B. D. Wines· 2 shared B. Greenhouse· 2 shared D. R. Drew· 2 shared E. Arinaitwe· 2 shared G. Dorsey· 2 shared I. Ssewanyana· 2 shared J. Rek· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

J.-A. Chan

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Author profile →

4 papers

Recent·Most cited

IgM plays a prominent role in naturally acquired immunity against Plasmodium falciparum gametocytes

J.-A. Chan, A. Lisboa-Pinto, S. Lu, A. Harris, M. W. Dixon, A. Thomas, D. R. Drew, N. Jayakrishnan, K. Larcher, M. Naghizadeh, D. H. Opi, L. Reiling, M. Theisen, K. Chelimo, M. Kaius-Ome, , J. Beeson

This study identifies IgM as a key antibody isotype in immune responses against Plasmodium falciparum gametocytes, showing its superior complement fixation activity compared to IgG.

bioRxiv · Jun 30, 2024 · PreprintImmunology

Age dependent changes in circulating Tfh cells influence the development of functional antibodies to malaria in children.

J.-A. Chan, J. Loughland, L. de la Parte, S. Okano, I. Ssewanyana, M. Nalubega, F. Nankya, K. Musinguzi, J. Rek, E. Arinaitwe, P. Tipping, P. Bourke, D. Andrew, N. Dooley, A. SheelaNair, , M. J. Boyle

The paper examines age-related changes in Tfh cells and their impact on antibody development against malaria in children, finding age-dependent shifts in Tfh cell subsets and antibody responses.

bioRxiv · Dec 12, 2021Immunology

Novel virus-like particle vaccine encoding the circumsporozoite protein of Plasmodium falciparum is immunogenic and induces functional antibody responses

L. Kurtovic, D. Wetzel, L. Reiling, D. R. Drew, C. Palmer, B. Kouskousis, E. Hanssen, B. D. Wines, P. M. Hogarth, M. Suckow, V. Jenzelewski, M. Piontek, J.-A. Chan, J. Beeson

This paper describes a novel virus-like particle vaccine using duck hepatitis B virus surface antigen to display Plasmodium falciparum CSP, showing improved immunogenicity and functional antibody responses in mice.

bioRxiv · Dec 14, 2020Immunology

Impact of a rapid decline in malaria transmission on antimalarial IgG subclasses and avidity

I. Ssewanyana, J. Rek, I. Rodriguez, L. Wu, E. Arinaitwe, J. Nankabirwa, J. Beeson, H. Mayanja- Kizza, P. Rosenthal, G. Dorsey, M. Kamya, C. Drakeley, B. Greenhouse, K. K. Tetteh

The paper examines how malaria transmission decline affects antimalarial IgG subclasses and avidity in Ugandans, finding age-related changes in IgG decay, subclass ratios, and avidity dynamics.

bioRxiv · Jun 26, 2020Immunology