Persistent biofluid small molecule alterations induced by Trypanosoma cruzi infection are not restored by antiparasitic treatment
D. A. Dean, J. Roach, R. Ulrich vonBargen, Y. Xiong, S. S. Kane, L. Klechka, K. Wheeler, M. Jimenez Sandoval, M. Lesani, E. Hossain, M. Katemauswa, M. Schaefer, M. Harris, S. Barron, Z. Liu, , L.-I. McCall
This study identifies persistent urine metabolome alterations in T. cruzi-infected mice that are not reversed by antiparasitic treatment, suggesting urine as a potential diagnostic tool for Chagas Disease.
bioRxiv · Jun 3, 2023Microbiology