Author

J. Roessler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Haghikia· 1 shared A. Lavin-Peter· 1 shared A. Markovski· 1 shared A. Robbi· 1 shared A. Timpanaro· 1 shared A. Tyshkovskiy· 1 shared B. J. H. Verhaar· 1 shared C. Piccand· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperPhysiology

A. Haghikia

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pneumonia induced rise in glucagon promotes endothelial damage and vascular thrombogenicity

P. Ramezani Rad, V. Nageswaran, L. Peters, L. Reinshagen, J. Roessler, S. Simmons, E. Asmus, C. Wittig, M. C. Brack, G. Nouailles, E. Van der Vorst, S. L. Maas, K. Sonnenschein, B. J. H. Verhaar, R. Szulcek, , A. Haghikia

This study shows that pneumonia increases glucagon levels, which damages endothelial cells and promotes blood clotting, leading to cardiovascular issues.

bioRxiv · May 3, 2024 · PreprintPhysiology

A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan

L. Jayne, A. Lavin-Peter, J. Roessler, A. Tyshkovskiy, M. Antoszewski, E. Ren, A. Markovski, S. Sun, H. Yao, V. G. Sankaran, V. N. Gladyshev, R. T. Brooke, S. Horvath, E. C. Griffith, S. Hrvatin

This study shows that inducing a torpor-like state in mice slows blood epigenetic aging and improves healthspan by reducing core body temperature.

bioRxiv · Mar 20, 2024Physiology

CAR T cells recognizing CD276 and Dual-CAR T cells against CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models

A. Timpanaro, C. Piccand, D. Dzhumashev, S. Anton-Joseph, J. Moser, A. Robbi, J. Roessler, M. Bernasconi

This study evaluates CD276 and FGFR4-targeting CAR T cells for rhabdomyosarcoma treatment, showing in vitro efficacy and in vivo tumor clearance, but limited effectiveness in low antigen expression tumors.

bioRxiv · Sep 5, 2023Cancer Biology