A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan
L. Jayne, A. Lavin-Peter, J. Roessler, A. Tyshkovskiy, M. Antoszewski, E. Ren, A. Markovski, S. Sun, H. Yao, V. G. Sankaran, V. N. Gladyshev, R. T. Brooke, S. Horvath, E. C. Griffith, S. Hrvatin
This study shows that inducing a torpor-like state in mice slows blood epigenetic aging and improves healthspan by reducing core body temperature.
bioRxiv · Mar 20, 2024Physiology