Cancer BiologybioRxiv
Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells
J. A. Thoms, K. Knezevic, G. Harvey…·J. E. Pimanda
The paper identifies a GATA2, TAL1, ERG regulatory circuit that promotes erythroid transition in both healthy and leukemic stem cells, showing its persistence in AML with minor alterations.
DOI 10.1182/blood.2020009707