Author

J. Staaf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. B. Brinkman· 1 shared A. Butler· 1 shared A. Ferrari· 1 shared A. Karlsson· 1 shared A. L. Richardson· 1 shared A. Sieuwerts· 1 shared A.-L. Borresen-Dale· 1 shared C. Frezza· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCancer Biology

A. B. Brinkman

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3 papers

Recent·Most cited

Multi-omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

J. Staaf, D. Ehinger, H. Brunnström, M. Jönsson, F. Rosengren, M. Kotevska, A. Karlsson, M. Aine, C. Frezza, M. Planck, E. Arbajian

The paper identifies metabolites and genes associated with squamous cell lung cancer using multi-omic data and validates their expression in tumors and cell lines.

bioRxiv · Apr 17, 2024Cancer Biology

Dysregulated gene expression through TP53 promoter swapping in osteosarcoma

K. H. Saba, V. Difilippo, M. Kovac, L. Cornmark, L. Magnusson, J. Nilsson, H. H. van den Bos, D. C. J. Spierings, M. Bidgoli, T. Jonson, V. P. Sumathi, O. Brosjo, J. Staaf, F. Foijer, E. Styring, , K. H. Nord

This study investigates how TP53 promoter swapping in osteosarcoma leads to dysregulated gene expression and oncogenic activation.

bioRxiv · Apr 20, 2020 · PreprintCancer Biology

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

A. B. Brinkman, S. Nik-Zainal, F. Simmer, F. G. Rodriguez-Gonzalez, M. Smid, L. B. Alexandrov, A. Butler, S. Martin, H. Davies, G. Dominik, X. Zou, M. Ramakrishna, J. Staaf, M. Ringner, A. Sieuwerts, , H. G. Stunnenberg

The paper shows PMDs are hypervariable in breast cancer and drive CGI hypermethylation, but do not significantly repress cancer genes.

bioRxiv · Nov 15, 2018Cancer Biology