J. Stadlmann

The wondrous and worrying diversity of the N-glycans of Chlorella food supplements

The paper analyzes N-glycan diversity in Chlorella supplements, finding mismatches between product labels and glycan patterns, highlighting concerns about product authenticity.

Tumor sialylation controls effective anti-cancer immunity in breast cancer

This study shows that tumor sialylation suppresses anti-cancer immunity in breast cancer by altering immune cell interactions and checkpoint ligands, and that inhibiting sialylation enhances immune response and therapy effectiveness.

Non-targeted isomer-sensitive N-glycome analysis reveals new layers of organ-specific diversity in mice.

The paper presents a method for analyzing N-glycome diversity in mice tissues, revealing tissue-specific glycosylation patterns and non-canonical structures.

Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor

This study engineers ACE2 glycosylation to enhance its binding to SARS-CoV-2 Spike protein, resulting in a more potent decoy receptor for COVID-19 treatment.

Community Evaluation of Glycoproteomics Informatics Solutions Reveals High-Performance Search Strategies of Serum N- and O-Glycopeptide Data

This study evaluates glycoproteomics software performance using human serum datasets, identifies high-performance strategies, and provides recommendations for improved analysis.

Comparative proteome signatures of trace samples by multiplexed Data-Independent Acquisition

The paper develops a method to quantitatively compare proteome signatures from ultra-low input samples using DIA-TMT multiplexing and a novel analysis pipeline.

Improved Sensitivity in Low-Input Proteomics using Micro-Pillar Array-based Chromatography

The paper benchmarks a micro-pillar array column against a conventional nano-flow HPLC column, showing improved sensitivity and peptide/protein identification in low-input proteomics.