Author

J. V. Zhang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:CITE-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

D. M. O'Rourke· 2 shared L. Zhang· 2 shared R. Thokala· 2 shared Y. Yin· 2 shared Z. A. Binder· 2 shared D. Kainth· 1 shared D. Y. Zhang· 1 shared E. X. Johns· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

D. M. O'Rourke

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 8, 2021

Locally secreted BiTEs complement CAR T cells by enhancing solid tumor killing

Y. Yin, J. Rodriguez, N. Li…·D. M. O'Rourke

This study shows that BiTE-secreting T cells outperform CAR T cells in killing glioma cells in vitro and in vivo, with enhanced cytotoxicity and tumor growth delay.

DOI 10.1101/2021.06.08.447602

mouseproteomics

𝕏 PostBluesky

Cancer BiologybioRxivFeb 4, 2021

High Affinity Chimeric Antigen Receptor with Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms

R. Thokala, Z. A. Binder, Y. Yin…·D. M. O'Rourke

This paper develops a CAR T cell with broad EGFR specificity to target multiple tumor clones and reduce antigen loss escape in glioblastoma.

DOI 10.3389/fonc.2021.664236

humanCITE-seq

𝕏 PostBluesky