Author

J. van Zon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Assay:organoid / primary culture· 2 Organism:C. elegans· 1 Research Focus:clustering· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

H. Clevers· 2 shared S. Tans· 2 shared X. Zheng· 2 shared Y. Goos· 2 shared B. Artegiani· 1 shared B. Demirbas· 1 shared D. Hendriks· 1 shared G. Huelsz-Prince· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiophysics

H. Clevers

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Control of C. elegans growth arrest by stochastic, yet synchronized DAF-16/FOXO nuclear translocation pulses

B. Demirbas, O. Filina, T. Louisse, Y. Goos, M. A. Sanchez-Romero, M. Olmedo, J. van Zon

The paper shows that DAF-16/FOXO translocation in C. elegans occurs in stochastic yet synchronized pulses, linking these dynamics to body-wide growth control.

bioRxiv · Jul 5, 2023 · PreprintCell Biology

Following cell type transitions in space and time by combining live-cell tracking and endpoint cell identity in intestinal organoids

X. Zheng, M. Betjes, Y. Goos, G. Huelsz-Prince, H. Clevers, J. van Zon, S. Tans

The paper introduces TypeTracker, a method combining live-cell tracking and endpoint cell identity to study differentiation trajectories in intestinal organoids, revealing new insights into cell type transitions and spatial organization.

bioRxiv · Jun 27, 2022 · PreprintBiophysics

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing

B. Artegiani, D. Hendriks, J. Beumer, R. Kok, X. Zheng, I. Joore, S. Chuva de Sousa Lopes, J. van Zon, S. Tans, H. Clevers

This paper introduces CRISPR-HOT, a method for efficient knock-in of exogenous DNA in human organoids without requiring homology templates or TP53 inactivation, and demonstrates its application in studying hepatocyte division and ploidy.

bioRxiv · Jan 15, 2020Cell Biology