Author

S. Chuva de Sousa Lopes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

B. Artegiani· 1 shared D. Hendriks· 1 shared H. Clevers· 1 shared I. Joore· 1 shared J. Beumer· 1 shared J. van Zon· 1 shared R. Kok· 1 shared S. Tans· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

B. Artegiani

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1 paper

Recent·Most cited

Cell BiologybioRxivJan 15, 2020

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing

B. Artegiani, D. Hendriks, J. Beumer…·H. Clevers

This paper introduces CRISPR-HOT, a method for efficient knock-in of exogenous DNA in human organoids without requiring homology templates or TP53 inactivation, and demonstrates its application in studying hepatocyte division and ploidy.

DOI 10.1038/s41556-020-0472-5

humanorganoid / primary culture

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