R. Baral

Experimental type 1 diabetes metabolically rejuvenates CD8+ T cells for improved control of tumor growth through an IGF1-IGF1R axis

This study shows that experimental type 1 diabetes enhances CD8+ T cell function via the IGF1-IGF1R axis, leading to better tumor control.

Transcriptomics and trans-organellar complementation reveal a limited signaling capacity of 12-cis-oxo-phytodienoic acid in wounded Arabidopsis

The paper investigates OPDA signaling in Arabidopsis by comparing transcriptomes of mutants and applying OPDA externally, finding limited signaling capacity and compartmentalization of endogenous OPDA.

Forage conservation is a neglected nitrous oxide source

This study investigates N2O emissions from forage conservation and finds it could be a significant source, with chlorate reducing emissions but other factors having no effect.

A General Mechanism for Initiating the General Stress Response in Bacteria

The paper identifies a coiled-coil linker mechanism in RsbU that activates the General Stress Response in bacteria by transducing signals from sensor domains.

Impaired aldehyde detoxification caused by a common human polymorphism promotes anti-bacterial immunity

The paper shows ALDH2 deficiency enhances anti-bacterial immunity by increasing aldehyde levels that kill pathogens and boost inflammatory responses.

Telomere DNA G-quadruplex folding within actively extending human telomerase

This study investigates how G-quadruplex (GQ) folding of nascent telomere DNA affects telomerase catalysis and dissociation kinetics.