Author

J. W. Smyth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

R. G. Gourdie· 2 shared C. Chuong· 1 shared C. M. Phillips· 1 shared D. R. King· 1 shared E. Nurmemmedov· 1 shared G. A. Blair· 1 shared G. S. Hoeker· 1 shared J. Dahlka· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

R. G. Gourdie

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 26, 2024

Increased interaction between connexin43 and microtubules is critical for glioblastoma stem-like cell maintenance and tumorigenicity.

J. W. Smyth, S. Guo, L. O'Rourke…·S. Lamouille

This study identifies a novel peptide, JM2, that disrupts Cx43-microtubule interaction in GBM stem-like cells, reducing their survival and tumorigenicity.

DOI 10.1101/2024.01.26.576347

humanproteomics

𝕏 PostBluesky

PathologybioRxivNov 29, 2022

Acute adenoviral infection elicits an arrhythmogenic substrate prior to myocarditis

R. L. Padget, M. J. Zeitz, G. A. Blair…·J. W. Smyth

This study shows adenoviral infection causes arrhythmogenic changes in the heart before significant immune response, through gap junction and ion channel dysfunction.

DOI 10.1161/circresaha.122.322437

mousehuman

𝕏 PostBluesky

PathologybioRxivMay 26, 2021

Adenovirus transduction to express human ACE2 causes obesity-specific morbidity in mice, impeding studies on the effect of host nutritional status on SARS-CoV-2 pathogenesis.

P. Rai, C. Chuong, T. LeRoith…·K. K. Hall

This study shows that adenovirus-mediated ACE2 expression in mice causes obesity-specific morbidity, complicating research on SARS-CoV-2 pathogenesis in different nutritional states.

DOI 10.1016/j.virol.2021.08.014

mousebulk RNA-seq

𝕏 PostBluesky