Author

R. Diskin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Assay:proteomics· 3 Research Focus:protein structure prediction· 2 Organism:virus· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. Cohen-Dvashi· 5 shared C. Kreer· 2 shared F. Klein· 2 shared H. Gruell· 2 shared H. Janicki· 2 shared K. Vanshylla· 2 shared M. Koch· 2 shared M. Korenkov· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersMicrobiology

H. Cohen-Dvashi

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The Structure of the Lujo Virus Spike Complex

M. Eilon-Ashkenazy, H. Cohen-Dvashi, S. Borni, R. Shaked, R. Calinsky, K. Levy, R. Diskin

The paper determines the cryo-EM structure of the Lujo virus spike complex, revealing how it binds neuropilin-2 and providing insights for vaccine design.

bioRxiv · Mar 13, 2024Microbiology

Dissecting the impact of somatic hypermutation on SARS-CoV-2 neutralization and viral escape

M. Korenkov, M. Zehner, H. Cohen-Dvashi, A. Borenstein-Katz, L. Kottege, H. Janicki, K. Vanshylla, T. Weber, H. Gruell, M. Koch, R. Diskin, C. Kreer, F. Klein

The paper reverts mutations in SARS-CoV-2 antibodies to study SHM's impact on neutralization, finding that some mutations are critical for neutralizing Omicron variants.

bioRxiv · May 9, 2023 · PreprintImmunology

Coronacept - a potent immunoadhesin against SARS-CoV-2

H. Cohen-Dvashi, J. Weinstein, M. Katz, M. Eilon, Y. Mor, A. Shimon, R. Strobelt, M. Shemesh, S. J. Fleishman, R. Diskin

The paper describes the design of a modified human ACE2 immunoadhesin with enhanced affinity for SARS-CoV-2 spike protein, showing its potential as an antiviral agent.

bioRxiv · Aug 12, 2020 · PreprintBioengineering

Longitudinal isolation of potent near-germline SARS-CoV-2-neutralizing antibodies from COVID-19 patients

C. Kreer, M. Zehner, T. Weber, C. Rohde, S. Halwe, M. S. Ercanoglu, L. Gieselmann, M. Korenkov, H. Gruell, P. Schommers, K. Vanshylla, V. Di Cristanziano, H. Janicki, R. Brinker, A. Ashurov, , F. Klein

This study isolates potent SARS-CoV-2-neutralizing antibodies from COVID-19 patients as early as 8 days post-diagnosis and identifies precursor B cells in healthy individuals.

bioRxiv · Jun 12, 2020Immunology

Expression of a recombinant, 4’-Phosphopantetheinylated, active M. tuberculosis Fatty acid Synthase I in E. coli

S. Baron, Y. Peleg, J. Grunwald, D. Morgenstern, N. Elad, M. Peretz, S. Albeck, Y. Levin, J. T. Welch, K. A. Deweerd, A. Schwartz, Y. Burstein, R. Diskin, Z. Shakked, O. Zimhony

This paper describes the expression and activation of Mtb FAS I in E. coli using AcpS, confirming its biochemical activity and structural properties.

bioRxiv · Aug 28, 2018Microbiology

Structural Basis for Receptor Recognition by Lujo Virus

H. Cohen-Dvashi, I. Kilimnik, R. Diskin

This study determines the structural basis of Lujo virus receptor recognition using X-ray crystallography, revealing its unique interaction with neuropilin-2 and evolutionary relationship to Old World arenaviruses.

bioRxiv · May 24, 2018Microbiology