Cancer BiologybioRxivPreprint
ROS induction as a strategy to target persister cancer cells with low metabolic activity in NRAS mutated melanoma
O. M. Eichhoff, C. I. Stoffel, J. Kaesler…·M. Levesque
The paper identifies ROS induction as a strategy to target MEK-inhibitor resistant NRAS-mutated melanoma cells by exploiting their quiescent metabolic state and elevated baseline ROS levels.
DOI 10.1101/2022.10.19.512839