Author

J. Wilcox

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

D. Bready· 3 shared D. G. Placantonakis· 3 shared G. Stephan· 3 shared J. D. Frenster· 3 shared N. Ravn-Boess· 3 shared B. Kieslich· 2 shared C. Wilde· 2 shared I. Liebscher· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

D. Bready

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The circulating immune cell landscape stratifies metastatic burden in breast cancer patients

S. Mangiola, R. Brown, J. Berthelet, S. Guleria, C. Liyanage, S. Ostrouska, J. Wilcox, M. Merdas, P. F. Larsen, C. Bell, J. Schroder, L. Mielke, J. Mariadason, S. Chang-Hao Tsao, Y. Chen, , B. Pal

This study identifies immune cell signatures in peripheral blood that correlate with metastatic burden in breast cancer patients using single-cell transcriptomics.

bioRxiv · Nov 1, 2023 · PreprintCancer Biology

The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability

N. Ravn-Boess, N. Roy, T. Hattori, D. Bready, H. Donaldson, C. Lawson, C. Lapierre, A. Korman, T. Rodrick, E. Liu, J. D. Frenster, G. Stephan, J. Wilcox, A. D. Corrado, J. Cai, , D. G. Placantonakis

This study identifies CD97 as a targetable vulnerability in glioblastoma through its role in tumor metabolism and signaling, supported by transcriptomic, proteomic, and functional analyses.

Cell Reports · Nov 1, 2023Peer-reviewedCancer Biology

PTK7 is a positive allosteric modulator of GPR133 (ADGRD1) signaling in GBM

J. D. Frenster, H. Erdjument-Bromage, W. Liu, G. Stephan, N. Ravn-Boess, D. Bready, J. Wilcox, B. Kieslich, M. Jankovic, C. Wilde, S. Horn, N. Straeter, I. Liebscher, T. Schoneberg, D. Fenyö, , D. G. Placantonakis

This study identifies PTK7 as a positive allosteric modulator of GPR133 signaling in glioblastoma, showing that their interaction enhances receptor activation and is relevant to tumor pathogenesis.

bioRxiv · Jun 15, 2022 · PreprintCell Biology

Dissociation of the intramolecularly cleaved N- and C-terminal fragments of the adhesion G protein-coupled receptor GPR133 (ADGRD1) increases canonical signaling

J. D. Frenster, G. Stephan, N. Ravn-Boess, D. Bready, J. Wilcox, B. Kieslich, C. Wilde, N. Sträter, G. R. Wiggin, I. Liebscher, T. Schöneberg, D. G. Placantonakis

This study shows that cleavage of GPR133 into NTF and CTF fragments at the plasma membrane enhances canonical signaling in GBM and HEK293T cells compared to an uncleavable mutant.

bioRxiv · Dec 8, 2020 · PreprintCell Biology