C. Bell

Increased Quadriceps Intermuscular Adipose Tissue in Chronic Liver Disease is Associated with an Altered Muscle Transcriptome compared with Healthy Age Matched Controls.

This study finds increased intermuscular adipose tissue in chronic liver disease patients compared to controls, associated with altered muscle gene expression and reduced muscle function.

DOG1 prevents AFPs activation by AHG1 to control dormancy separately from ABA core signaling

This study identifies DOG1's role in preventing AFPs activation by AHG1, controlling dormancy independently of ABA core signaling.

The NAPstar family of NADP redox state sensors highlights glutathione as the primary mediator of anti-oxidative electron flux

The paper introduces NAPstar biosensors to measure NADP redox states and finds glutathione mediates anti-oxidative electron flux across eukaryotes.

Systemically targeting monocytic MDSCs using dendrimers and their cell-level biodistribution kinetics

This study examines how hydroxyl dendrimers are taken up by M-MDSCs in tumor and lymphoid organs, showing differential uptake based on dendrimer functionality and serum proteins.

The circulating immune cell landscape stratifies metastatic burden in breast cancer patients

This study identifies immune cell signatures in peripheral blood that correlate with metastatic burden in breast cancer patients using single-cell transcriptomics.

Germline determinants of the prostate tumor genome

The paper identifies germline-determined quantitative trait loci (dQTLs) that influence somatic mutational features in prostate cancer, revealing their impact on tumor epigenome, transcriptome, and proteome.

In vitro selection of a microbial consortium predictive of synergistic functioning along multiple ecosystem scales

The paper assesses how different microbial consortia affect phosphorus solubilization and plant growth, finding that combined species outperform individual species.

Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

The paper identifies FOXA1 reprogramming in NEPC and shows its role in maintaining NE lineage features through epigenomic profiling.

Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dys-regulation of Epithelial-Mesenchymal Transition and subcellular re-localization of Beta-Catenin

This study performs a proteomic analysis of Dnmt1 hypomorph colorectal cancer cells, revealing dysregulation of EMT and subcellular relocalization of Beta-Catenin.