Author

J. Z. He

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Biology Disciplines

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

H. Jiang· 1 shared J. Yu· 1 shared J. Zhao· 1 shared L. A. Yang· 1 shared L. Shan· 1 shared L. Xu· 1 shared S. S. Chen· 1 shared X. M. Liu· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

H. Jiang

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1 paper

Recent·Most cited

Cancer BiologybioRxivOct 1, 2019

Defining relative mutational difficulty to understand cancer formation and prevention

H. Jiang, L. Shan, J. Yu…·L. A. Yang

The paper introduces a method to predict the functionality of low-frequency missense mutations by integrating mutation counts with relative mutational difficulty, revealing functional p53 mutations and potential cancer prevention strategies.

DOI 10.1038/s41421-020-0177-8

humanwhole-genome sequencing

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