Deep learning methods for designing proteins scaffolding functional sites
J. Wang, S. Lisanza, D. Juergens, D. Tischer, I. Anishchenko, M. Baek, J. L. Watson, J.-H. Chun, L. F. Milles, J. Dauparas, M. Exposit, W. Yang, A. Saragovi, S. Ovchinnikov, D. Baker
This paper introduces two deep learning methods for designing proteins with specific functional sites, showing they can generate diverse proteins with desired properties.
bioRxiv · Nov 10, 2021Biochemistry