Author

J.-I. Abe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. Rizvi· 1 shared C. Brown· 1 shared C. Zod· 1 shared J. Abraham· 1 shared K. Chen· 1 shared L. Reed· 1 shared M. Lee· 1 shared S. Kotla· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Rizvi

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1 paper

Recent·Most cited

Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of lysine demethylation and oxidative phosphorylation

S. S. Dhar, C. Brown, A. Rizvi, L. Reed, S. Kotla, C. Zod, J. Abraham, J.-I. Abe, V. Rajaram, K. Chen, M. Lee

This study shows that heterozygous Kmt2d loss promotes medulloblastoma by enhancing tumor-promoting programs and that combining LSD1 inhibition with oxidative phosphorylation blockade reduces tumorigenicity.

bioRxiv · Oct 29, 2023 · PreprintCancer Biology