Author

L. Reed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Rizvi· 1 shared B. Barksby· 1 shared C. Brown· 1 shared C. Griffiths· 1 shared C. S. Chialvo· 1 shared C. Zod· 1 shared D. Manas· 1 shared D. Mann· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. Rizvi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of lysine demethylation and oxidative phosphorylation

S. S. Dhar, C. Brown, A. Rizvi, L. Reed, S. Kotla, C. Zod, J. Abraham, J.-I. Abe, V. Rajaram, K. Chen, M. Lee

This study shows that heterozygous Kmt2d loss promotes medulloblastoma by enhancing tumor-promoting programs and that combining LSD1 inhibition with oxidative phosphorylation blockade reduces tumorigenicity.

bioRxiv · Oct 29, 2023 · PreprintCancer Biology

Investigating the phylogenetic history of toxin tolerance in mushroom-feeding Drosophila

T. Erlenbach, L. Haynes, O. Fish, J. Beveridge, E. Bingolo, S.-A. Giambrone, G. Kropelin, S. Rudisill, P. Chialvo, L. Reed, K. Dyer, C. S. Chialvo

This study investigates the evolution of cyclopeptide tolerance in mushroom-feeding Drosophila by combining phylogenetic analysis and functional assays, revealing that tolerance was ancestral and lost multiple times.

bioRxiv · Aug 3, 2023 · PreprintEvolutionary Biology

A novel bioreactor technology for modelling fibrosis in human and rodent precision-cut liver slices.

H. Paish, L. Reed, H. Brown, M. Bryan, O. Govaere, J. Leslie, B. Barksby, J. French, S. White, D. Manas, S. Robinson, G. Spoletini, C. Griffiths, D. Mann, L. Borthwick, , F. Oakley

This paper develops a bioreactor system that extends the viability of precision-cut liver slices (PCLS) to 6 days under normoxic conditions and demonstrates its use in modeling fibrogenesis and testing anti-fibrotic drugs.

bioRxiv · May 25, 2018Cell Biology