Metabolic vulnerability is a target of the antineoplastic effect of breastfeeding.
Edmund Charles Jenkins, Mrittika Chattopadhyay, K. Andersen, Soma Seal, Nicola Francesco Tavella, Joanne Stone, Sabine Heitzeneder, Crystal Lee Mackall, Rachel Brody, Claus Oxvig, Doris Germain
The paper shows lactating serum has anti-cancer effects targeting PAPP-A-expressing cells and identifies CRF as a key mediator of this effect through mitochondrial inhibition.
bioRxiv · Mar 5, 2026 · PreprintCancer Biology