Author

K. Bianchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

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Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Nagano· 1 shared B. Selvarajah· 1 shared B. Yaman· 1 shared C. Chelala· 1 shared C. Frezza· 1 shared D. Guillotin· 1 shared E. Wilcz-Villega· 1 shared G. Contento· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Nagano

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis

G. Contento, J.-A. A. Wilson, B. Selvarajah, M. Plate, D. Guillotin, V. Morales, M. Trevisani, V. Pitozzi, K. Bianchi, R. C. Chambers

This study shows that pyruvate metabolism affects fibroblast response to GLS1 inhibition during fibrosis, suggesting combined targeting of pyruvate metabolism and glutaminolysis as a therapeutic strategy.

bioRxiv · Jan 30, 2024Cell Biology

The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism

R. Xu, W. Jones, E. Wilcz-Villega, S. Costa, V. Rajeeve, R. B. Bentham, K. Bryson, A. Nagano, B. Yaman, S. Olendo Barasa, Y. Wang, C. Chelala, P. Cutillas, G. Szabadkai, C. Frezza, K. Bianchi

This study shows that IKKε, a breast cancer oncogene, reprograms mitochondrial function and serine metabolism independently of its canonical signaling role, promoting cancer cell proliferation.

bioRxiv · Nov 26, 2019Cancer Biology