Human Digital Twin: Automated Cell Type Distance Computation and 3D Atlas Construction in Multiplexed Skin Biopsies
S. Ghose, Y. Ju, E. McDonough, J. Ho, A. Karunamurthy, C. Chadwick, S. Cho, R. Rose, A. Corwin, C. Surrette, J. S. Martinez, E. Williams, A. Sood, Y. Al-Kofahi, L. D. Falo, , F. Ginty
The paper develops a 3D workflow to analyze multiplexed skin biopsy data, revealing age-related changes in DNA repair and immune cell ratios.
bioRxiv · Mar 30, 2022Cell Biology