PhysiologybioRxivPreprint
LRH-1 NUTRIGENOMICS: The Provision of Lauric Acid Results in the Endogenous Production of the Liver Receptor Homolog-1 Ligand, Dilauroylphosphatidylcholine, and LRH-1 Transactivation
K. C. Klatt, S. Zhang, O. V. Malysheva…·M. A. Caudill
This study shows that lauric acid intake leads to endogenous production of DLPC, an LRH-1 ligand, and enhances LRH-1 transcriptional activity in multiple tissues.