Author

K. Chawla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Farbos· 1 shared A. Jeffries· 1 shared A. Lee· 1 shared A. Singh· 1 shared A. Singhal· 1 shared B. Lee· 1 shared C. Grady· 1 shared D. Chaudhary· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. Farbos

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2 papers

Recent·Most cited

Phage-induced efflux down-regulation boosts antibiotic efficacy

S. Kraus, U. Lapinska, K. Chawla, E. Baker, E. Attrill, P. ONeill, A. Farbos, A. Jeffries, E. Galyov, S. Korbsrisate, K. Barnes, S. Harding, K. Tsaneva-Atanasova, M. Blaskovich, S. Pagliara

This study shows that phage presence reduces antibiotic efflux in bacteria, enhancing antibiotic efficacy and enabling lower concentrations for treatment.

bioRxiv · Sep 21, 2023Microbiology

Disulfiram inhibits M. tuberculosis growth by altering methionine pool, redox status and host-immune response

D. Chaudhary, M. Marzuki, A. Lee, R. Bouzeyen, A. Singh, T. P. Gosain, S. Kidwai, C. Grady, K. Tsotetsi, K. Chawla, F. Shihui, J. Lum, S. K. Gupta, N. Agarwal, L. Tsenova, , A. Singhal

This study identifies disulfiram as a novel inhibitor of Mtb's methionine biosynthesis, showing anti-tubercular effects through redox disruption and immune modulation.

bioRxiv · Sep 1, 2020 · PreprintMicrobiology