MicrobiologybioRxiv
SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial derived cells and cardiomyocytes
Y. Li, D. Renner, C. E. Comar…·S. R. Weiss
This study investigates how SARS-CoV-2 interacts with host antiviral pathways in respiratory and cardiac cells, finding it activates OAS-RNase L and PKR but not IFN, contrasting with MERS-CoV.
DOI 10.1073/pnas.2022643118