E. Morrisey

Endothelial SARS-CoV-2 infection is not the underlying cause of COVID19-associated vascular pathology in mice

This study shows that endothelial SARS-CoV-2 infection does not significantly contribute to COVID-19-associated vascular pathology in mice.

TGFβ controls alveolar type 1 epithelial cell plasticity and alveolar matrisome gene transcription

This study shows TGFβ signaling is essential for maintaining alveolar type 1 cell fate and regulates the alveolar matrisome through integrin transcription and mechanotransduction.

SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice

Microstructured hydrogels to guide self-assembly and function of lung alveolospheres

This paper introduces a hydrogel-based method to culture lung alveolospheres without Matrigel, reducing heterogeneity while maintaining cell fate.

SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial derived cells and cardiomyocytes

This study investigates how SARS-CoV-2 interacts with host antiviral pathways in respiratory and cardiac cells, finding it activates OAS-RNase L and PKR but not IFN, contrasting with MERS-CoV.