Author

K. D. Browne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:development & morphogenesis· 4 Organism:rat· 4 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. K. Cullen· 5 shared F. A. Laimo· 3 shared H. I. Chen· 2 shared J. C. Burrell· 2 shared J. C. Maggiore· 2 shared L. A. Struzyna· 2 shared W. J. Gordian-Velez· 2 shared Z. Ali· 2 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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5 shared papersBioengineering

D. K. Cullen

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6 papers

Recent·Most cited

Dopaminergic axon tracts within a hyaluronic acid hydrogel encasement for implantation to restore the nigrostriatal pathway

W. J. Gordian-Velez, K. D. Browne, J. H. Galarraga, J. E. Duda, R. A. Espana, H. I. Chen, J. A. Burdick, D. K. Cullen

This paper develops a hyaluronic acid hydrogel-based tissue-engineered nigrostriatal pathway to restore dopamine function in Parkinson's disease by improving axon growth and reducing inflammation.

bioRxiv · Jul 3, 2021Bioengineering

Marked differences in local bone remodeling in response to different marrow stimulation techniques in a large animal

H. M. Zlotnick, R. C. Locke, B. D. Stoeckl, J. M. Patel, S. Gupta, K. D. Browne, J. Koh, J. L. Carey, R. Mauck

This study compares three marrow stimulation techniques in minipigs, finding that needle-puncture best preserves subchondral bone compared to drilling and microfracture.

bioRxiv · Feb 26, 2021Bioengineering

Tissue Engineered Axon-Based Living Scaffolds Promote Survival of Spinal Cord Motor Neurons Following Peripheral Nerve Repair

J. C. Maggiore, J. C. Burrell, K. D. Browne, K. C. Katiyar, F. A. Laimo, Z. Ali, H. M. Kaplan, J. M. Rosen, D. K. Cullen

This study compares living and non-living scaffolds for nerve repair, finding that tissue-engineered grafts (TENGs) preserve motor neuron health and function as effectively as autografts.

bioRxiv · Sep 22, 2020Bioengineering

Pre-Innervated Tissue Engineered Muscle Promotes a Pro-Regenerative Microenvironment Following Volumetric Muscle Loss

S. DAS, K. D. BROWNE, F. A. LAIMO, J. C. MAGGIORE, H. Kaisaier, C. A. Aguilar, Z. S. ALI, F. MOURKIOTI, D. K. CULLEN

This study develops pre-innervated tissue engineered muscle constructs to enhance regeneration after volumetric muscle loss in rats.

bioRxiv · Nov 13, 2019Bioengineering

Tissue Engineered Axon Tracts Serve as Living Scaffolds to Accelerate Axonal Regeneration and Functional Recovery Following Peripheral Nerve Injury in Rats

K. Katiyar, L. A. Struzyna, J. P. Morand, J. C. Burrell, B. Clements, F. A. Laimo, K. D. Browne, J. Kohn, Z. Ali, H. C. Ledebur, D. H. Smith, D. K. Cullen

This study shows tissue-engineered axon tracts enhance axonal regeneration and functional recovery in rats with sciatic nerve injuries, outperforming nerve guidance tubes and matching autografts.

bioRxiv · May 31, 2019Bioengineering

Three-dimensional human axon tracts derived from cerebral organoids

D. K. Cullen, L. A. Struzyna, D. Jgamadze, W. J. Gordian-Velez, J. Lim, K. L. Wofford, K. D. Browne, H. I. Chen

This paper describes the generation of three-dimensional human axon tracts from cerebral organoids, which can be transplanted and mimic brain connectivity features.

bioRxiv · Jan 25, 2018Bioengineering