Functional single-cell profiling identifies that exosomes are associated with increased immune cell infiltration in non-metastatic breast cancer
M. Fathi, R. Joseph, J. R. T. Adolacion, M. Martinez-Paniagua, X. An, K. Gabrusiewicz, S. A. Mani, N. Varadarajan
The paper develops a single-cell technique to profile exosome secretion in breast cancer cells and finds that non-metastatic cells secrete more exosomes, which correlates with better prognosis and immune infiltration.
bioRxiv · Dec 14, 2020Cancer Biology