K. Graham

Liquid-like condensates that bind actin drive filament polymerization and bundling

The paper shows that actin-binding proteins forming liquid-like condensates can polymerize and bundle actin filaments, expanding the known set of proteins capable of this function.

Liquid-like condensates mediate competition between actin branching and bundling

This study shows that liquid-like condensates containing both actin branching and bundling proteins can modulate the competition between these processes, leading to organized actin structures similar to those in migrating cells.

Novel YAP1/TAZ pathway inhibitors identified through phenotypic screening with potent anti-tumor activity via blockade of GGTase-I / Rho-GTPase signaling

Kinetic trapping organizes actin filaments within liquid-like protein droplets

This study uses computational modeling and experiments to show that kinetic trapping of actin filaments in VASP droplets leads to different network architectures like shells and rings.

Pseudomonas aeruginosa TfpW is a multifunctional D-Araf glycosyltransferase and oligosaccharyltransferase

This paper identifies TfpW as a multifunctional enzyme in Pseudomonas aeruginosa that performs glycosylation, translocation, and polymerization of D-Araf in type IV pili.

Development of a knowledge translation platform for ataxia: Impact on readers and volunteer contributors

This study evaluates the impact of SCAsource, a knowledge translation platform for ataxia research, on readers and volunteer contributors after one year.